Since 2012 she is a permanent member of the curatorial team at the "Pushkinskaya-10" — the oldest non-governmental artist-run institution in Russia founded in 1989. She also works as an independent curator in collaboration with art institutions in Russia and abroad. In 2013 Anastasia Patsey founded the "2,04 gallery", which functions as a shared art laboratory and project incubator for emerging art professionals.
She is co-founder and board member of the "Paideia School of interpretation of contemporary art", an independent educational initiative launched in 2014. Since 2012 she is directing the St. Petersburg International Art Residency, which regularly hosts interdisciplinary art professionals from all over the world.
In Fall 2015 Anastasia Patsey was offered the directorial position at the St. Petersburg Museum of nonconformist art that she currently holds. Anastasia Patsey teaches at the St. Petersburg State Stieglitz Art Academy and is a guest lecturer at the National Research University Higher School of Economics, the Pushkin Leningrad State University and the St. Petersburg State Polytechnic University.
Her academic research is dedicated to artistic self-organisation, art residencies, cultural mobility and modern nomadism. Since 2020 she teaches at the St. Petersburg State Stieglitz Art Academy.